Macromolecular X-Ray Crystallography

Cyclic trihydroxamic acid derivatives

Probability / Macromolecular X-Ray Crystallography / Hydrogen Bonding / Molecular Conformation / Triazines / Acids

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Theoretical studies on farnesyltransferase: The distances paradox explained

Macromolecular X-Ray Crystallography / Biological Sciences / Mathematical Sciences / DFT / Peptides / Zinc / Proteins / Cysteine / Protein Conformation / Structure Function / Zinc / Proteins / Cysteine / Protein Conformation / Structure Function

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Theoretical studies on farnesyltransferase: The distances paradox explained

Macromolecular X-Ray Crystallography / Biological Sciences / Mathematical Sciences / DFT / Peptides / Zinc / Proteins / Cysteine / Protein Conformation / Structure Function / Zinc / Proteins / Cysteine / Protein Conformation / Structure Function

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UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries

Natural Products / Mass Spectrometry / Macromolecular X-Ray Crystallography / Biological Sciences / Arizona / CHEMICAL SCIENCES / Diterpenes / Molecular Conformation / Flavones / Hesperidin / Molecular Structure / Plant Leaves / CHEMICAL SCIENCES / Diterpenes / Molecular Conformation / Flavones / Hesperidin / Molecular Structure / Plant Leaves

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A novel proteinmineral interface

Molecular Biology / Macromolecular X-Ray Crystallography / Crystal structure / Animals / Iron / Metals / High Resolution / Protein Domains / Hafnium / Metal ion / Protein Conformation / University of Southern California / Recombinant Proteins / Protein Binding / Binding Site / Molecular Structure / Neisseria gonorrhoeae / Metals / High Resolution / Protein Domains / Hafnium / Metal ion / Protein Conformation / University of Southern California / Recombinant Proteins / Protein Binding / Binding Site / Molecular Structure / Neisseria gonorrhoeae

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A novel protein–mineral interface

Molecular Biology / Macromolecular X-Ray Crystallography / Crystal structure / Animals / Iron / Metals / High Resolution / Protein Domains / Hafnium / Metal ion / Protein Conformation / University of Southern California / Recombinant Proteins / Protein Binding / Binding Site / Molecular Structure / Neisseria gonorrhoeae / Metals / High Resolution / Protein Domains / Hafnium / Metal ion / Protein Conformation / University of Southern California / Recombinant Proteins / Protein Binding / Binding Site / Molecular Structure / Neisseria gonorrhoeae

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Crystal structure of human esterase D: a potential genetic marker of retinoblastoma

Genetics / Physiology / Protein Folding / Crystallization / Macromolecular X-Ray Crystallography / Protein Structure and Function / Crystal structure / Gene Mapping / Humans / Sequence alignment / Human Body / Medical Physiology / Enzyme / Dimensional / Retinoblastoma / Active site / Enzyme activity / Amino Acid Sequence / Rutherford Backscattering Spectroscopy / X Ray Crystallography / Early Diagnosis / Genetic Markers / Biochemistry and cell biology / Molecular Sequence Data / Protein Structure and Function / Crystal structure / Gene Mapping / Humans / Sequence alignment / Human Body / Medical Physiology / Enzyme / Dimensional / Retinoblastoma / Active site / Enzyme activity / Amino Acid Sequence / Rutherford Backscattering Spectroscopy / X Ray Crystallography / Early Diagnosis / Genetic Markers / Biochemistry and cell biology / Molecular Sequence Data

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Multiple Endocrine Neoplasia Type1: An Unusual Presentation

Genetics / Molecular Biology / Surgical Oncology / Gene expression / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / Mutagenesis / Genetic Testing / Mutation / Mice / Female / Animals / Male / Gene / Pedigree / Risk factors / Phenotype / Insulinoma / Clinical Sciences / Molecular cloning / Gen / Genotype / Adult / Pituitary Adenoma / Disease Progression / Risk Factors / Hyperparathyroidism / Primary hyperparathyroidism / Amino Acid Substitution Rates / X ray Computed Tomography / Adenoma / Endocrinologist / Hypercalcemia / Pituitary Neoplasms / Biological Sciences / Humans / Mutagenesis / Genetic Testing / Mutation / Mice / Female / Animals / Male / Gene / Pedigree / Risk factors / Phenotype / Insulinoma / Clinical Sciences / Molecular cloning / Gen / Genotype / Adult / Pituitary Adenoma / Disease Progression / Risk Factors / Hyperparathyroidism / Primary hyperparathyroidism / Amino Acid Substitution Rates / X ray Computed Tomography / Adenoma / Endocrinologist / Hypercalcemia / Pituitary Neoplasms

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Antibacterial Diterpenes from Plectranthus ernstii

Natural Products / Macromolecular X-Ray Crystallography / Biological Sciences / CHEMICAL SCIENCES / Great Britain / Anti-Bacterial Agents / Diterpenes / Natural / Microbial Sensitivity Tests / Molecular Conformation / Methicillin Resistant Staphylococcus Aureus / Molecular Structure / Anti-Bacterial Agents / Diterpenes / Natural / Microbial Sensitivity Tests / Molecular Conformation / Methicillin Resistant Staphylococcus Aureus / Molecular Structure

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N-(Sulfonamido)alkyl[tetrahydro-1 H-benzo[ e]indol-2-yl]amines: potent antagonists of human neuropeptide Y Y5 receptor

Organic Chemistry / Macromolecular X-Ray Crystallography / Humans / Neuropeptide Y / Bioorganic and medicinal Chemistry / Molecular Structure

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Proteoglycan sequence

Mass Spectrometry / Sequence Analysis / Macromolecular X-Ray Crystallography / Humans / Computer Simulation / Animals / Proteoglycans / Biochemistry and cell biology / Animals / Proteoglycans / Biochemistry and cell biology

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase

Molecular Dynamics Simulation / Kinetics / Biological Chemistry / Macromolecular X-Ray Crystallography / Biological Sciences / Mutation / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Protein Binding / Nucleotides / Poliovirus / Mutation / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Protein Binding / Nucleotides / Poliovirus

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Copper (II) Complexes of [1,2,4]Triazolo [1,5-a]Pyrimidine Derivatives as Potential Anti-Parasitic Agents

Drug metabolism / Macrophages / Leishmania / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Energy Metabolism / Cercopithecus aethiops / Copper / Mice / Animals / Drug Design / Trypanosoma Cruzi / Triazoles / NAD / Organometallic Compounds / Vero cells / Energy Metabolism / Cercopithecus aethiops / Copper / Mice / Animals / Drug Design / Trypanosoma Cruzi / Triazoles / NAD / Organometallic Compounds / Vero cells

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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UPLC-MS-ELSD-PDA as a Powerful Dereplication Tool to Facilitate Compound Identification from Small-Molecule Natural Product Libraries

Natural Products / Mass Spectrometry / Macromolecular X-Ray Crystallography / Biological Sciences / Arizona / CHEMICAL SCIENCES / Diterpenes / Molecular Conformation / Flavones / Hesperidin / Molecular Structure / Plant Leaves / CHEMICAL SCIENCES / Diterpenes / Molecular Conformation / Flavones / Hesperidin / Molecular Structure / Plant Leaves

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